Source: http://www.thehollywoodgossip.com/2013/02/melissa-king-video-its-totally-her-right/
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Thursday, February 28, 2013
Munoz leads after 1st round at HSBC Champions
SINGAPORE (AP) ? Spain's Azahara Munoz shot a 7-under 65 Thursday for a two-stroke lead after the first round of the HSBC Women's Champions, which features 17 of the top 20 LPGA players.
Munoz played in the day's first group and finished with seven birdies. Five players at Sentosa Golf Club shared second at 67: Stacy Lewis, Karin Sjodin, Lizette Salas, Pornanong Phatlum and Sun Young Yoo.
Munoz is coming off her strongest season on tour, winning her first title at the Sybase Match Play Championship and enjoying nine top-10 finishes.
"I don't know what it is but my best three rounds on tour have been first tee time," she said. "I really like it. You don't have to wait, it's super nice, the greens are perfect. I think it gets me going."
Paula Creamer was in a four-way tie at 68 despite an injured right shoulder from a car accident. The five-car accident happened on the way to the airport after the Honda LPGA tournament in Thailand.
Two other players, Ai Miyazato and Suzann Pettersen, sustained minor injuries in the crash. Miyazato pulled out of the HSBC Champions on Wednesday, citing stiffness in her back, neck and shoulder.
Also at 68 were top-ranked Yani Tseng of Taiwan, Danielle Kang and Chella Choi.
Tseng, a five-time major winner, was five shots off the lead before sinking a 25-foot putt for eagle on the 18th hole. Tseng hasn't won a tournament in nearly a year, but she has started the 2013 season with a second-place finish at the Australian Open and a tie for third at Thailand last weekend.
She said she made a bet with her manager, Naya Hsu, on Thursday morning to better motivate herself. If she scored a 68 or better, Hsu agreed to go skydiving with her in Hawaii.
"When that putt dropped in, I was so happy," Tseng said. "I was looking for her. I saw her face, I think she's going to cry.
"I think it feels good because I haven't had that feeling for a long time," she said. "The last two weeks, kind of a little rushed, trying to play well on the first day. And today I've been patient because I know it's only the first day, I still have three days left."
Creamer was just happy to be on the course after her accident. She said she jammed her shoulder when she hit the dashboard of the car and suffered whiplash after slamming her head off the headrest.
"At the beginning of the round, I really couldn't feel my right side and I didn't know if I was going to be able to even go," she said. "I thought if I could get through the first five holes, I would be OK. I have no expectations whatsoever this week," she said.
Second-ranked Na Yeon Choi, who is trying to close in on Tseng's No. 1 ranking, shot a 69. Michelle Wie, South Korea's Jiyai Shin and Australia's Karrie Webb were at 71, with Pettersen at 73. Defending champion Angela Stanford had a quadruple bogey on the par-4 13th en route to a 76.
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Praising children for their personal qualities may backfire
Feb. 27, 2013 ? Praising children, especially those with low self-esteem, for their personal qualities rather than their efforts may make them feel more ashamed when they fail, according to new research published by the American Psychological Association.
"This type of personal praise may backfire. What may seem like common sense can sometimes lead adults astray in their attempts to help children with low self-esteem feel better about themselves," said lead researcher Eddie Brummelman, MS, of Utrecht University in the Netherlands. The study was published online in the Journal of Experimental Psychology: General.
The study found that children with low self-esteem often received praise for their personal qualities, and that type of praise can trigger greater feelings of shame from failure and may lead to a diminished sense of self-worth.
In one experiment, 357 parents in the Netherlands, ranging in age from 29 to 66, read six descriptions of hypothetical children -- three with high self-esteem (e.g., "Lisa usually likes the kind of person she is,") and three with low self-esteem (e.g., "Sarah is often unhappy with herself"). The participants were told to write down the praise they would give the child for completing an activity, such as drawing a picture. On average, the parents gave children with low self-esteem more than twice as much praise directed at personal qualities (e.g., "You're a great artist!") than they gave to children with high self-esteem. They also were more likely to praise children with high self-esteem for their efforts. (e.g., "You did a great job drawing!")
"Adults may feel that praising children for their inherent qualities helps combat low self-esteem, but it might convey to children that they are valued as a person only when they succeed," Brummelman said. "When children subsequently fail, they may infer they are unworthy."
A second experiment illustrated that point. The researchers recruited 313 children (54 percent girls) ranging in age from 8 to 13 from five public elementary schools in the Netherlands. Several days before the experiment, the students completed a standard test that measures self-esteem. For the experiment, the children were told they would play an online reaction time game against a student from another school and that a webmaster would be monitoring their performance via the Internet. In reality, the computer controlled the outcome of the game, and the children were divided into winners and losers, including groups that received praise for themselves, praise for their efforts, or no praise.
In the group where the children were praised for their personal qualities, the webmaster wrote, "Wow, you're great!" after the students completed one round of the game, whereas the children whose actions were praised were told, "Wow, you did a great job!" The group that received no praise served as a control. After a second round, the children were told they either won or lost the game, and they completed a survey about their feelings of shame. Children who lost the game experienced a sharp increase in shame if they had been praised for their personal qualities, especially if they had low self-esteem, compared to the other groups.
The researchers theorized that children who are praised for their efforts may not associate their self-worth with success, so failure is viewed as a temporary setback or a lack of effort rather than a flaw in their character. Brummelman said the study results may apply generally to children from most Western countries, including the United States, but the results may be less applicable to Eastern countries, such as China, where adults may use different approaches for praising children.
The differences between praising a person and praising his or her efforts may be very subtle, but those differences can have a big impact on children's self-esteem, said study co-author Brad Bushman, PhD, a communication and psychology professor at The Ohio State University. Therefore, parents and teachers should focus on praising children for their efforts rather than their personal qualities, he added.
"In general, it is better to praise the behavior rather than the individual," Bushman said. "If you praise the individual and he fails, it can cause shame and may inadvertently send the message, 'I am a bad person.'"
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The above story is reprinted from materials provided by American Psychological Association (APA), via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Eddie Brummelman, Sander Thomaes, Geertjan Overbeek, Bram Orobio de Castro, Marcel A. van den Hout, Brad J. Bushman. On Feeding Those Hungry for Praise: Person Praise Backfires in Children With Low Self-Esteem.. Journal of Experimental Psychology: General, 2013; DOI: 10.1037/a0031917
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/Z265gvNvFew/130227183316.htm
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Wednesday, February 27, 2013
France's Hollande juggles trade and rights in Moscow
PARIS (Reuters) - President Francois Hollande will aim to balance French concerns over Russia's human rights record with a push to boost trade ties during a debut Moscow visit on Thursday that could prove a diplomatic obstacle course.
An encounter in Paris last June between the newly-elected Socialist Hollande and Russia's Vladimir Putin bristled with tension, unlike the cozy meetings between Putin and Hollande's conservative predecessors Nicolas Sarkozy and Jacques Chirac.
Aides on both sides want to avoid the full-frontal clash on rights that marked German Chancellor Angela Merkel's trip to Moscow last year, when she accused Moscow of stifling dissent.
Moreover, with the French economy edging closer to recession and domestic demand moribund, Hollande needs all the outside help he can get to kickstart growth, and will be pushing for Russian business to step up investment in France.
Yet everything from Moscow's support of Syrian leader Bashar al-Assad in defiance of the West to Putin's very public relish at actor Gerard Depardieu's decision to take Russian nationality for tax reasons means the scope for misunderstandings is great.
"You can get on with someone without loving them," veteran Russia specialist Helene Carrere d'Encausse said of the strained pragmatism she saw defining the visit, whose high-point is an 1100 GMT joint news conference with Hollande and Putin on.
Hollande aides insist that, aside from Syria, the positions of Paris and Moscow converge in several areas - notably on Mali, where Russia has backed a U.N. resolution which is a key part of French efforts to extricate its soldiers and put African troops in the front line against al Qaeda allies.
RIGHTS RECORD
Russia sees Tuesday's move by major powers to offer Iran some sanctions relief in return for a halt of some atomic work as a sign that France and other Western states are moving closer to its thinking on an issue that has divided the U.N. Security Council for years.
"In bilateral ties I see no major problems," said Alexei Pushkov, head of foreign affairs committee in the Russian parliament's lower chamber.
"From my contacts with the French lawmakers I get the impression they have a calm attitude towards Russia. Of course there is come criticism, but not to the extent that can be heard in the U.S. Congress or the German Bundestag," he added.
French officials insist Putin's embrace of Depardieu after his decision to seek exile from French taxes on the rich will not jar relations - even with the actor's outing this weekend to the Chechnya region where rights groups accuse security services of extrajudicial killings and other abuses.
But Hollande is under pressure at home to raise human rights concerns including the fate of Putin critics such as Mikhail Khodorkovsky, 49, once Russia's richest man and now serving 13 years jail on fraud and tax evasion charges.
"The last year has been the worst for human rights in Russia in recent memory, and Hollande should not miss this chance to persuade Putin to turn things around," said Rachel Denber of New York-based Human Rights Watch, pointing to new laws which she said restricted public assembly and Internet content in Russia.
The two leaders may broach delicate energy issues, with the European Union seeking to wind down its gas reliance on Russia and Moscow angry over EU efforts to force dominant suppliers such as Russia's Gazprom to sell off infrastructure.
But Paris is keener to focus on raising Russian investment in France, which at around one billion euros only accounts for a 12th of the value of French investment in Russia.
While no major deal is due to be announced, small economic cooperation pacts, plans to facilitate visas and student exchanges are likely to be announced.
(Additional reporting by Gabriela Baczynska in Moscow; Writing by Mark John; Editing by Jon Boyle)
Source: http://news.yahoo.com/frances-hollande-juggles-trade-rights-moscow-131910312.html
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HideIPVPN
HideIPVPN is a personal VPN service that is easy to use, hides your online activity from eavesdroppers, and allows you to spoof your IP address to view content that is restricted to certain geographic areas. VPN technology encrypts all traffic leaving the computer online and ensures data remains hidden from third parties even when on an open wireless network. It has a nice balance of basic features and advanced capabilities, and most users will find the pricing plan that fits their needs.
I downloaded the Windows installer appropriate for my operating system from the website and was up and running within minutes. HideIPVPN supports Windows, Mac OS X, Linux, Android, and iOS devices, which is still unusual in this space. Users can also use the VPN credentials to set up proxy servers within the Web browser and other applications, such as Skype.
Like Private Internet Access, the service also has custom instructions for users interested in installing the service on non-standard hardware, but at the moment the list includes only the Nokia N900 and a network router running the popular (and hackable) DD-WRT firmware. All in all, it is a solid VPN service to consider, so long as you don't need servers outside Germany, the Netherlands, the United States, and United Kingdom. There is also a "Canada-only" plan.
A Refresher on How VPN Services Work
Your Internet service provider assigns your computer an IP address. A geo-location lookup reveals the geographic location of the ISP or the data center containing the server assigning the address. Anyone can perform this lookup and estimate your location. There have also been recent cases when the courts forced Internet companies and ISPs to hand over user information when presented with the IP address.
With a VPN service, users hide in plain sight, as the assigned IP address comes from a server stored in a data center somewhere else.
The service creates an encrypted tunnel between the computer and the destination website or network, and all data flows through that tunnel. Even if you are using a coffee-shop hotspot, you can log into your email or access other accounts without worrying about someone eavesdropping or intercepting data. It's important to remember that the data is only protected while in transit; if the destination site is not using HTTPS, that part of the connection is unencrypted. Anyone who is sitting at that point of exit can see and harvest that information, and there are fairly complicated timing algorithms out there to identify user activity.
Pricing Plans
Similar to many of its competitors, HideIPVPN uses OpenVPN SSL technology to create its encrypted tunnel, although SSTP and PPTP connections are also possible. Users can buy packages giving them access to a pool of IP addresses only in one specific country (United States, United Kingdom, Canada, or Germany) for just $5.99 a month, or buy a bundled plan to access servers in up to four countries, the US, UK, the Netherlands, and Germany, for $9.99.? The most comprehensive plan, including all four countries, is $14.99, which puts it slightly on the pricier end among other VPN services.
Most VPN services block users from using peer-to-peer services or accessing files via BitTorrent while connected. Offenders usually get blocked from the service. HideIPVPN treats the problem slightly differently. Instead of blocking the users entirely, the company offers a dedicated P2P/BitTorrent plan for $7.99, where users connect to Dutch and German servers and start downloading. Users can easily upgrade or downgrade the plan each month.
Users interested in trying out the service before buying can download the trial, which is capped at three hours of usage. It would have been nice to see a more full-fledged trial version, especially since three hours online (that's three hours after creating the account, not three hours of usage) is pretty limiting. The free trial version does allow users to connect to any of the servers in US, UK, Netherlands and Germany, although all P2P and BitTorrent activity remains restricted to Dutch and German networks. It appears there are eight servers available in each region.
Getting Started
I tried out HideIPVPN on a trip, as well as from a local coffeeshop and on our testing network. Performance and the available features are on par with similar offerings, even though some of its advanced features nudge HideIPVPN into the top tier of VPN services.
HideIPVPN sent me a VPN username and password after I registered my email address with the site. The step-by-step instructions for HideIPVPN clearly lay out the process for the newest users. Since HideIPVPN supports the OpenVPN protocol, the installer also adds the TAP-WIN32 adapter, in the same way as VPN Direct and ProXPN installed the adapter?Next: Using HideIPVPN, Performance
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/YTvWUsIfi7Q/0,2817,2415695,00.asp
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Herm?s, Chanel tap Travel + Leisure for lifestyle push - Luxury Daily ...
Travel + Leisure March issue
Herm?s and Chanel are standing out against the travel-focused pages of American Express Publishing?s Travel + Leisure March issue to showcase their affluent brand lifestyle.
Travel advertisers including Trump Hotel Collection, Oceania Cruises and Oberoi Hotels & Resorts take up quite a few pages in the issue. This month?s editorial focus is a Rome travel guide and the 2013 Design Awards.
?Travel + Leisure always has a high-style quotient, and the ninth annual Travel + Leisure Design Awards in this month?s issue heightens that element even more,? said Jay Meyer, vice president and publisher of Travel + Leisure, New York.
?The Design Awards highlight the best new examples of design across a range of categories covering everything from hotels and museums to travel accessories and clothing,? he said.
.jpg&contenttype=jpeg "Sign up for Luxury Daily!")
Travel + Leisure has a total circulation of 988,648.
Across the pond
The first ad in the issue is a two-page spread of Herm?s? spring sporting campaign. The ad shows a woman wearing an oversized scarf positioned upon a bicycle.
Herm?s ad?
TAG Heuer?s ad starts off the table of contents.
Celebrity Cruises, Mexico?s Nizuc Resort & Spa, Oceania Cruises, India?s The Leela Palaces Hotels and Resorts, Trump Hotel Collection, Oberoi Hotels & Resorts and other advertisers took out placements among the first editorial pages leading up to the Design Awards section.
Trump ad?
The Travel + Leisure Design Awards feature best museum St?del Museum Frankfurt; best resort Tierra Patagonia Hotel & Spa in Torres del Paine, Chile; best public space Franklin D. Roosevelt Four Freedoms Park in New York; best transportation London Bus; and best retail space Sweet Alchemy by Stelios Parliaros in Athens among other accolades.
Succeeding editorial features cover a wellness retreat in the Thai island of Koh Samui, the current mood in Hamburg, peer-to-peer tours in Los Angeles, the ?definitive guide? to Rome, 12 family vacation ideas and villa rentals.
Rome guide?
Chanel closes out the issue with its latest J12 Chronograph ad.
Chanel ad?
Out of the box
Quite often luxury marketers use ad placements and media partnerships to venture outside of their brand category.
For example, luxury jewelry advertisers along with high-end home brands are targeting readers of Veranda?s March/April issue, which saw a 4.29 percent increase in ad pages since the year-ago period.
Chanel, Rolex, Tiffany & Co. and Patek Philippe are pushing jewelry and watches in a magazine customarily dominated by ads from home and design brands. Advertisers in new categories are looking to Veranda to align with the interests of today?s affluent consumer after the magazine shifted its front-of-book editorial to have a lifestyle focus (see story).
In addition, department store chain Saks Fifth Avenue partnered with American Express Publishing?s Departures magazine to raise awareness for its hand-tailored fall menswear collections through an advertorial and event in Bal Harbour, FL.
The advertorial called ?The Artisans? appeared exclusively in the December issue of Departures.
Saks and Departures also hosted an event to draw male consumers and showcase brands such as Canali, Corneliani, Kiton, Ralph Lauren, Saks Fifth Avenue Private Label and Tod?s (see story).
Now, fashion and jewelry brands are likely tapping the aspirational vibe of Travel + Leisure to reach affluent consumers in a certain frame of mind.
?The March issue has a good mix of luxury advertising, from watches and beauty to automotive,? Mr. Meyer said. ?New luxury business in this issue includes Chanel J12 watches, Herm?s, TAG Heuer, Lanc?me and the Lincoln Motor Company.?
Final Take
Tricia Carr, editorial assistant on Luxury Daily, New York
Tricia Carr is an editorial assistant on Luxury Daily. Her beats are apparel and accessories, arts and entertainment, education, food and beverage, fragrance and personal care, government, healthcare, home furnishings, jewelry, legal/privacy and nonprofits. Reach her at tricia@napean.com.
Like this article? Sign up for a free subscription to Luxury Daily's must-read newsletters. Click here!
Related content: None Found
Tags: American Express Publishing, Design Awards, Hermes, Jay Meyer, luxury, luxury marketing, Media/publishing, Print, Travel + Leisure, Trump Hotel Collection
You can leave a response, or trackback from your own site.Source: http://www.luxurydaily.com/hermes-chanel-tap-travel-leisure-for-lifestyle-push/
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Research suggests scientists have overestimated capacity of wind farms to generate power
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 26-Feb-2013[ | E-mail |
Share ] Contact: Buffie Stephens
buffiestephens@uncc.edu
704-687-5830
University of North Carolina at Charlotte
People think of wind as an energy source with few limits, offering an unending power source with distinct capacity advantages over sources that deplete, such as fossil fuel.
Yet, new research in mesoscale atmospheric modeling by UNC Charlotte's Amanda S. Adams and Harvard University's David W. Keith, published Monday in the journal Environmental Research Letters, suggests that the power capacity of large-scale wind farms may have been significantly overestimated.
With large-scale wind farms, as many as hundreds of turbines mounted on tall towers and connected to the electrical grid capture the kinetic energy of the wind. Each wind turbine creates a "wind shadow" behind it, in which the turning blades slow the air. In an effort to reduce the impact of the wind shadows, wind farms space the turbines apart, while still locating as many turbines as they can on the land.
Current estimates of the global wind power resource over land range from 56 to 400 terawatts. Most of these estimates assume implicitly that the turbines extracting the wind energy have little impact on the atmosphere and, therefore, little effect on the energy production.
The new research says that scientists have underestimated the impact that large numbers of wind turbines have on energy production within large farms. Estimates of wind capacity that ignore the effect of wind turbine drag on local winds have assumed that wind power production of 2 and 4 watts per square meter could be sustained over large areas.
The new modeling results suggest that the generating capacity is more likely limited to about 1 watt per square meter at wind farms that are larger than 100 square kilometers.
"It's easy to mistake the term renewable with the term unlimited when discussing energy," Adams said. "Just because you can keep generating new energy from a source does not mean you can generate energy in an unlimited amount."
The research suggests the potential for wind energy could be significantly less than previously thought.
"It's important to take into account all factors impacting the wind energy, so we can assess the capacity of this critical power resource," Adams said. "One of the inherent challenges is how harvesting the resource changes it, making it difficult to accurately calculate how much energy can be produced. The modeling we have done provides information that can help in the understanding of our ability to count on renewable energy sources."
The research also considers the impact of wind energy production on temperatures and by extension possibly climate. Wind farms change the natural wind shear and produce various scales of turbulence. Higher potential temperatures are mixed downward due to this turbulence and result in low level warming, the research indicates.
"Our research suggests that how densely the turbines are placed affects not only energy production but also environmental impacts," Adams said. "We see this impact on average temperatures not only at large-scale farms, but also in small-density wind farms. Some things to consider are the magnitude of temperature changes and also the size of the area affected. We think these findings indicate that additional research is needed in these areas."
The Natural Sciences and Engineering Research Council of Canada funded the research.
Adams' primary research interests focus on mesoscale phenomena, processes, and modeling with an emphasis on phenomena that involve boundary layer processes and/or topographic influences. In recent years, she and her research group at UNC Charlotte have focused on the link between small-scale processes and climate, particularly at the atmosphere and earth surface interface. Her research group concentrates primarily on question at the interface between energy, weather and climate.
Current questions her group is addressing include: How will large scale wind energy development impact the Great Plains low level jet? What are the meteorological conditions that lead to wind turbine icing? How does temperature variability in urban areas impact electricity demand? Can we quantify the risks of off shore wind turbines to hurricanes? The energy-related research that Adams' group is conducting includes collaborations with San Diego Gas & Electric, Xcel Energy, and the Weather Underground.
###
Buffie Stephens, 704-687-5830 buffiestephens@uncc.edu
Source: Amanda Adams, 704-687-5984 manda.adams@uncc.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 26-Feb-2013[ | E-mail |
Share ] Contact: Buffie Stephens
buffiestephens@uncc.edu
704-687-5830
University of North Carolina at Charlotte
People think of wind as an energy source with few limits, offering an unending power source with distinct capacity advantages over sources that deplete, such as fossil fuel.
Yet, new research in mesoscale atmospheric modeling by UNC Charlotte's Amanda S. Adams and Harvard University's David W. Keith, published Monday in the journal Environmental Research Letters, suggests that the power capacity of large-scale wind farms may have been significantly overestimated.
With large-scale wind farms, as many as hundreds of turbines mounted on tall towers and connected to the electrical grid capture the kinetic energy of the wind. Each wind turbine creates a "wind shadow" behind it, in which the turning blades slow the air. In an effort to reduce the impact of the wind shadows, wind farms space the turbines apart, while still locating as many turbines as they can on the land.
Current estimates of the global wind power resource over land range from 56 to 400 terawatts. Most of these estimates assume implicitly that the turbines extracting the wind energy have little impact on the atmosphere and, therefore, little effect on the energy production.
The new research says that scientists have underestimated the impact that large numbers of wind turbines have on energy production within large farms. Estimates of wind capacity that ignore the effect of wind turbine drag on local winds have assumed that wind power production of 2 and 4 watts per square meter could be sustained over large areas.
The new modeling results suggest that the generating capacity is more likely limited to about 1 watt per square meter at wind farms that are larger than 100 square kilometers.
"It's easy to mistake the term renewable with the term unlimited when discussing energy," Adams said. "Just because you can keep generating new energy from a source does not mean you can generate energy in an unlimited amount."
The research suggests the potential for wind energy could be significantly less than previously thought.
"It's important to take into account all factors impacting the wind energy, so we can assess the capacity of this critical power resource," Adams said. "One of the inherent challenges is how harvesting the resource changes it, making it difficult to accurately calculate how much energy can be produced. The modeling we have done provides information that can help in the understanding of our ability to count on renewable energy sources."
The research also considers the impact of wind energy production on temperatures and by extension possibly climate. Wind farms change the natural wind shear and produce various scales of turbulence. Higher potential temperatures are mixed downward due to this turbulence and result in low level warming, the research indicates.
"Our research suggests that how densely the turbines are placed affects not only energy production but also environmental impacts," Adams said. "We see this impact on average temperatures not only at large-scale farms, but also in small-density wind farms. Some things to consider are the magnitude of temperature changes and also the size of the area affected. We think these findings indicate that additional research is needed in these areas."
The Natural Sciences and Engineering Research Council of Canada funded the research.
Adams' primary research interests focus on mesoscale phenomena, processes, and modeling with an emphasis on phenomena that involve boundary layer processes and/or topographic influences. In recent years, she and her research group at UNC Charlotte have focused on the link between small-scale processes and climate, particularly at the atmosphere and earth surface interface. Her research group concentrates primarily on question at the interface between energy, weather and climate.
Current questions her group is addressing include: How will large scale wind energy development impact the Great Plains low level jet? What are the meteorological conditions that lead to wind turbine icing? How does temperature variability in urban areas impact electricity demand? Can we quantify the risks of off shore wind turbines to hurricanes? The energy-related research that Adams' group is conducting includes collaborations with San Diego Gas & Electric, Xcel Energy, and the Weather Underground.
###
Buffie Stephens, 704-687-5830 buffiestephens@uncc.edu
Source: Amanda Adams, 704-687-5984 manda.adams@uncc.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-02/uonc-rss022613.php
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Tuesday, February 26, 2013
Ikea withdraws meatballs in more than 20 countries
STOCKHOLM (AP) ? Swedish furniture giant Ikea became entangled in Europe's widening meat scandal Monday, forced to withdraw meatballs from stores across Europe amid suspicions that they contained horse meat.
Stores in the U.S. and Canada were not affected, Ikea said.
The company reacted after authorities in the Czech Republic said they had detected horse DNA in tests of 1-kilogram (2.2-pound) packs of frozen meatballs that were labeled as beef and pork. The Czech State Veterinary Administration said it tested two batches of Ikea meatballs and only one of them contained horse meat. It did not say how much.
Meatballs from the same batch had been sent from a Swedish supplier to 12 other European countries ? Slovakia, Hungary, France, Britain, Portugal, the Netherlands, Belgium, Spain, Italy, Greece, Cyprus and Ireland ? and would be pulled off the shelves in all of them, Ikea said.
Later Monday, the company expanded the withdrawals to stores in 21 European countries and in Hong Kong, Thailand and the Dominican Republic, all of which were getting meatballs from the same Swedish supplier.
Ikea spokeswoman Ylva Magnusson said that included most European countries, but not Russia and Norway, which use local suppliers. Stores in Poland and Switzerland use both local suppliers and the Swedish one, but would now only use locally produced meatballs, she said.
"This is an extraordinary effort to ensure that no one is worried," Magnusson told The Associated Press.
She added that two weeks ago Ikea tested a range of frozen food products, including meatballs, and found no traces of horse meat. The company plans to conduct its own tests to "validate" the Czech results, she said.
Ikea's North America branch said the U.S. stores get their meatballs from a U.S. supplier.
"Based on the results of our mapping, we can confirm that the contents of the meatballs follow the Ikea recipe and contain only beef and pork from animals raised in the U.S. and Canada," Ikea North America spokeswoman Mona Astra Liss said in a statement.
Ikea is known for its assemble-it-yourself furniture but its trademark blue-and-yellow megastores also have cafeteria-style restaurants offering Swedish dishes such as meatballs served with boiled or mashed potatoes, gravy and lingonberry jam.
European Union officials met Monday to discuss tougher food labeling rules after the discovery of horse meat in a wide range of frozen supermarket meals that were supposed to contain beef or pork. So far those foods include meatballs, burgers, kebabs, lasagna, pizza, tortelloni, ravioli, empanadas and meat pies, among other items.
Authorities say the scandal is a case of fraudulent labeling but does not pose a health risk.
Gunnar Dafgard AB, a family-owned frozen foods company in southwestern Sweden that supplies Ikea's meatballs in Europe, posted a brief statement on its website saying "the batch in question has been blocked and we are investigating the situation."
Spokesman Ola Larsson said the company was conducting its own DNA tests and wouldn't comment further until it has those results.
Sweden's food safety authority said it wasn't taking any action but was waiting for Czech authorities to specify the quantity of horsemeat detected.
"If it's less than 1 percent it could mean that they handled horsemeat at the same facility. If it's more, we assess that it's been mixed into the product," said Karin Cerenius of Sweden's National Food Agency.
The Czech authority said a total of 760 kilograms (1,675 pounds) of the meatballs were stopped from reaching the shelves. It also said it found horse meat in beef burgers imported from Poland during random tests of food products.
"Unfortunately, the testing method we use detects just the quality ... the presence or non-presence of horse DNA," said Jan Vana, a senior official at the State Veterinary Administration. "At the moment, we can't say the quantity of it."
Spanish authorities, meanwhile, announced that traces of horse meat were found in a beef cannelloni product by one of the brands of Nestle, a Switzerland-based food giant.
In a statement on its website, Nestle Spain said it was withdrawing six "La Cocinera" products and one "Buitoni" product from store shelves. It said it was taking the action after traces of horse meat were found in beef bought from a supplier in Spain and that it was taking legal action against the company.
Processed food products ? a business segment with traditionally low margins that often leads producers to hunt for the cheapest suppliers ? often contain ingredients from multiple suppliers in different countries, who themselves at times subcontract production to others, making it hard to monitor every link in the production chain.
Standardized DNA checks with meat suppliers or more stringent labeling rules on disclosing the origin of processed food's ingredients will add costs that producers will most likely hand over to consumers, making food more expensive.
The scandal has created a split in the European Union between nations like Britain, which see further rules as a protectionist hindrance of free trade under the 27-nation bloc's single market, and those calling for tougher regulation, including Austria and Germany.
"Consumers have every right to the greatest-possible transparency," German Agriculture Minister Ilse Aigner said.
At the meeting in Brussels, several EU agriculture ministers called upon the Commission, the bloc's executive arm, to speed up presenting a proposal on tougher regulation by this summer.
The scandal began in Ireland in mid-January when the country announced the results of its first-ever DNA tests on beef products. It tested frozen beef burgers taken from store shelves and found that more than a third of brands at five supermarkets contained at least a trace of horse. The sample of one brand sold by the British supermarket kingpin Tesco had more than 25 percent horse meat.
___
Associated Press writers Juergen Baetz in Brussels, Karel Janicek in Prague and Ciaran Giles in Madrid contributed to this report.
Source: http://news.yahoo.com/ikea-withdraws-meatballs-more-20-countries-211231901--finance.html
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BlackBerry launches the Z10 in India for $800
The BB10-toting BlackBerry Z10 has just been unveiled in India, priced at Rs 43,490 ($800) for an unlocked unit. Coinciding with the announcement, the BlackBerry Music Store has also gone live in the country starting today, offering a mix of local and international music. Support for local languages aside, the app offerings have been given an Indian flavor with the inclusion of country-specific goodies spanning various genres including news, banking, travel, entertainment and lifestyle. The subcontinent is quite important for the company formerly known as RIM, and its devices are still popular in the region, despite taking a beating in market share recently (see coverage), courtesy the BBM service that makes them the go-to smartphones for those hooked on to the instant messaging platform. However, the Z10's sticker price puts it in the same league as the 16GB iPhone 5 and HTC's full-HD Butterfly (both costing roughly $50 more), and it remains to be seen how the price-sensitive Indian market will react to the new entrant.
Filed under: Cellphones, Mobile, Blackberry
Source: http://www.engadget.com/2013/02/25/blackberry-z10-india/
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Monday, February 25, 2013
Host MacFarlane's humor gets mixed reception
Kevin Winter / Getty Images
By Randee Dawn, TODAY contributor
Seth MacFarlane is best known as the creator of the often risque "Family Guy" series, not generally the kind of biography touted by an Oscar host. With a reported billion people watching worldwide, some Oscar fans wondered what MacFarlane would pull out of his bag of tricks Sunday night.
Everything, it turned out, and anything -- including a series of initial jokes that elicited as many gasps and groans as laughs. Sure, he made a solid base hit with his first words: "And the quest to make Tommy Lee Jones laugh begins now" (cut to the man whose poker face became a meme during the Golden Globes chuckling gently). But a reference to Chris Brown and Rihanna's relationship problems (joking that they considered bloody and violent "Django Unchained" "a date movie") crossed a line for some, as did his comparing the multiple uses of the n-word in "Django" to "Mel Gibson's voice mails."
Fortuntately, Capt. Kirk arrived to try and save the night. An enormous screen descended from the top of the stage featuring William Shatner in full "Star Trek" regalia, pointing out to MacFarlane that his jokes were "tasteless" and "inappropriate."
Shatner/Kirk showed the first of several "future clips" and headlines indicating that MacFarlane had ruined the telecast: First, a performance of "We Saw Your Boobs," a song that named a number of actresses who went half-dressed in various films. (Cut to pre-filmed clips of actresses giving him dirty looks for pointing out that at some point, billions of movie fans out there saw, well, their boobs.)
And no surprise, a boob singing songs about boobs won over the crowd, temporarily. It didn't necessarily win over the viewing audience, however, and spawned the first of what would be an evening's worth of blog posts and Tweets questioning whether MacFarlane was sexist. Buzzfeed made a list, ?The Atlantic Wire said the monologue was "maybe racist and sexist," and of course the Twitterverse weighed in.?
But all of that was happening off-camera, and back on stage MacFarlane knew he had to "fix" the future. So he launched into "The Way You Look Tonight" as Channing Tatum and Charlize Theron danced in classic Fred-and-Ginger style behind him, a move that didn't fix everything. Shatner next had to explain why MacFarlane's sock-puppet reenactment of "Flight," in which he wore a brown sock to represent Denzel Washington, bombed at the "future" Oscars.
"You're a white guy in 2013," said Shatner to MacFarlane. "You can't wear black hand."
And that's when the mood of the crowd sank again. The truth: White guys doing racial humor, no matter how gentle, still makes everyone uncomfortable. So MacFarlane led into another older tune -- MacFarlane, Joseph Gordon-Levitt and Daniel Radcliffe hoofing it to "High Hopes," a song popularized in 1959.
It still wasn't quite enough, said Shatner, to make MacFarlane an acceptable host -- and another future clip featured him dressed as Sally Field's character "The Flying Nun," chatting up Field backstage, ultimately making out with her and driving off in a "Smokey and the Bandit"-style Trans Am. "I went home with Sally Field, that's awesome!" he said.
But without Field there to get her Oscar, Shatner told him, Amy Adams "ran up and grabbed it ... they tried to take it from her and she bit a guy." So, the final attempt: MacFarlane had to give the crowds a showstopper of an opener. One more big song and dance number: "Beauty and the Beast's" peppy "Be Our Guest." And that seemed to do it -- Shatner's screen vanished, and projected across the back of the stage, the new headline: "Best Oscars ever, says everyone except Entertainment Weekly."
Cut to the new Tommy Lee Jones of the evening, the unsmiling nominee Joaquin Phoenix. So maybe Entertainment Weekly is in good company.?
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First Presbyterian Church of Freehold celebrates 175th anniversary
Sorry, Readability was unable to parse this page for content.
Source: http://www.app.com/article/20130223/NJNEWS/302230035/1004/NEWS01&source=rss
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Radioactive waste leaking from tanks at Washington state nuclear site
SEATTLE (Reuters) - Six underground storage tanks at the Hanford Nuclear Reservation along the Columbia River in Washington state were recently found to be leaking radioactive waste, but there is no immediate risk to human health, state and federal officials said on Friday.
The seeping waste adds to decades of soil contamination caused by leaking storage tanks at Hanford in the past and threatens to further taint groundwater below the site but poses no near-term danger of polluting the Columbia River, officials said.
The newly discovered leaks were revealed by Governor Jay Inslee a week after the U.S. Energy Department disclosed that radioactive waste was found to be escaping from one tank at Hanford.
Inslee said he was informed on Friday by outgoing U.S. Energy Secretary Steven Chu that a total of six of the aging, single-walled tanks were leaking radioactive waste.
"There is no immediate or near-term health risk associated with these newly discovered leaks, which are more than 5 miles from the Columbia River," Inslee said in a statement released by his office. "But nonetheless this is disturbing news for all Washingtonians."
The governor said Chu told him that his department initially missed the other five leaking tanks because staff there did not adequately analyze data.
"This certainly raises serious questions about the integrity of all 149 single-shell tanks with radioactive liquid and sludge at Hanford," he said.
The Energy Department issued a brief statement acknowledging that six waste tanks were found to be leaking and adding that there was "no immediate public health risk."
Four of the tanks in question, including the two biggest of the group, are known to have leaked waste in the past as well, Suzanne Dahl, the tank waste treatment manager for the state Department of Ecology, told Reuters.
"It points to the age of the tanks and how there's going to be an increased probability of this happening in the future," she said. "When waste is in the tanks, it's manageable. Once it's out of the tanks and in the soil, it's much harder to manage it, remove it, and down the road you're adding to contamination in the groundwater that already exists."
DECLINING LIQUID LEVELS
The Energy Department said a week ago that declining liquid levels in one tank at Hanford showed it was leaking at a rate of 150 to 300 gallons (568 to 1,136 liters) per year.
It subsequently informed state officials that a second, larger tank was leaking at about the same rate, while the four smaller tanks were leaking at a rate of about 15 gallons per year, Dahl said.
The Department of Energy said last week that monitoring wells have identified no significant changes in concentrations of chemicals or radionuclides in the soil.
The two biggest tanks at issue have capacities of about 750,000 gallons and 500,000 gallons, while the four others are designed to hold up to 55,000 gallons, Dahl said. All were constructed many decades ago.
The 586-square-mile (1,518-square-km) Hanford Nuclear Reservation was established near the town of Hanford in 1943 as part of the Manhattan Project, the U.S. government program that developed the first atomic bombs.
Production of plutonium materials at the site continued through the Cold War and ended there in 1989 as work shifted to cleanup of nuclear and chemical waste at Hanford, considered one of the largest and most complex such projects in the country.
Weapons production at the site resulted in more than 43 million cubic yards of radioactive waste and 130 million cubic yards of contaminated soil and debris, according to the U.S. Environmental Protection Agency, which says that approximately 475 billion gallons of contaminated water have been discharged into the soil.
As part of the cleanup, as much remaining liquid waste as possible was pumped out of the older single-shell tanks into sturdier double-walled tanks in a process completed in 2005, Dahl said.
But sludge, mud-like waste and pockets of liquid remained behind in the older tanks, and it is that material that was found to be seeping in the soil again from six tanks, she said. According to the DOE, one of those tanks currently holds about 447,000 gallons of radioactive sludge.
Under the multibillion-dollar cleanup plan, the waste from the storage tanks will eventually be processed in a special treatment plant that will immobilize the waste in a glass-like material that can be safely disposed of underground in stainless steel canisters.
But Dahl said construction of the waste treatment plant was still years away.
(Reporting by Eric Johnson, Steve Gorman and Dan Whitcomb; Writing by Dan Whitcomb and Steve Gorman; Editing by Paul Thomasch, Cynthia Johnston, Andre Grenon, Lisa Shumaker and Paul Simao)
Source: http://news.yahoo.com/radioactive-waste-leaking-six-tanks-washington-state-nuclear-034828611.html
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Sunday, February 24, 2013
Steve Jobs Art: A Birthday Tribute - Business Insider
Summary
Apple Inc. is an American multinational corporation that designs and markets consumer electronics, computer software, and personal computers. The company's best-known hardware products include the Macintosh line of computers... More ?Source: http://www.businessinsider.com/steve-jobs-art-a-birthday-tribute-2013-2
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news Art and Entertainment: Music Industry Is About To Change !
At the beginning of 2000's, the music business, in particular the communities of hiphop and rnb, resulted in the rise of what we now call the "super music producers", accounting for frontrunners: Dr. Dre, Timbaland, Rodney Jerkins or even The Neptunes.
What is meant by a "super producer"? So, the most reliable interpretation of their distinction with a "simple" producer would take the demonstration of what we call a "supermodel" in fashion, for instance Cindy Crawford, Claudia Schiffer or Naomi Campbell. You know these prominent fashion models as well as anybody else and you can see them on almost all the catwalks. To be brief: safe values.
This was the very same thing in the music industry: there have been "big" producers, risk free, that driven entirely the projects and were needed by the most well-known singers or rappers. It was really less hazardous for record labels to use a popular music producer in contrast to a novice. The known one produced a more than a few of triumphant singles, in theory. Given that right at that time ordinarily big names sold discs.
However, the music business, since the start of the decade has totally changed. First, many people don't actually buy cd nowadays.
Consequently the record labels offer less budget for a project. And of course, record companies will no longer be willing to put in money between $ 100 000 to $ 300 000 for just one single beat, as was the case through the golden years of music producers. The cd not sell and the internet grows. To surmount not legal downloading of their artists, record companies develop or merge with statutory download applications and just try to force their presence on the cyberspace, that has been escaping their control for so long.
But the rise up of the web in addition has permitted the ascent of many of unknown producers as good as, if not superior to, "Super Producers".
Those producers have paying attention to the developments of the Internet, that has facilitated these to sell their beats online. Giving them to reach and work with performers on a local scale as well as a worldwide one. A producer from New york city can advertise beats to any one in Japan. It is now more easier for them to obtain a good recognition or have a career. For the artists, this makes a big difference! They can buy beats online at home for their album, EP and also mixtape for reasonable prices; far from those practiced by the "super producers".
Record labels pay a specific attention to this modern business. They buy beats online as well. And nowadays we can notice that a few internet based producers are getting signed by majors.
The golden time period of super producers such as the era of super model fades away slowly and gradually, allowing way to this brand new sector driven by producers who, often, have not a single thing to envy to the "super producers".
Source: http://newsartentertainment.blogspot.com/2013/02/music-industry-is-about-to-change.html
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HTC One for Sprint spotted with FCC approval
The HTC One just made its first official appearance (unless you count its brief showing by Peter Chou at the year-end party as "official") on Tuesday, and while we haven't been given any specific availability in the US, its models are at least starting to receive approval from the FCC. This particular model sports Sprint-specific LTE (band 25) and also includes 802.11ac support, a telltale sign that this is indeed the Now Network's One. The fact that the docs detail the test unit as a production model is a solid indication that HTC's flagship is well on its way to Overland Park, and soon. And it doesn't appear to be alone, either; two other variants snuck through the process of federal approval, one with quad-band LTE (bands 2, 4, 5 and 17) and another with dual-band (bands 4 and 17). It seems that HTC isn't wasting any time on bringing its attack to US shores.
Filed under: Cellphones, Wireless, Mobile, HTC, Sprint
Source: FCC
Source: http://www.engadget.com/2013/02/22/htc-one-sprint-fcc/
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Saturday, February 23, 2013
Pakistan condemns deadly bombings in India
Press TV ? February 22, 2013
Pakistan has condemned the twin deadly bomb explosions in the Indian city of Hyderabad which left at least 20 people dead.
?Terrorism in all its forms and manifestations constitutes one of the most serious threats to international peace and security,? Pakistan?s Foreign Ministry said in a statement.
?Being itself a victim of terrorism, Pakistan fully understands and shares the pain and agony of the people of India. Our prayers and thoughts are with the families of victims of this terrorist attack,? the statement added.
A bomb went off on Thursday evening near a popular cinema called Venkatadri Cinema in the district of Dilsukh Nagar which is one of the largest commercial centers in Hyderabad. Minutes later, a second blast took place next to a nearby bus stop.
Indian police have said that they had been informed of plans for a possible attack in the Hyderabad area last year.
?We interrogated two militants [from the Indian Mujahideen group], who said they had recced (reconnoitered) various spots in Delhi, Mumbai, Hyderabad, Pune for a possible attack. One of the places they mentioned was Dilsukh Nagar, which was hit last night,? said S.N. Shrivastava, a Delhi police commissioner.
According to reports, since 1992, at least nine bomb blasts have rocked Heydarabad including three bomb explosions in 2007 that claimed the lives of at least 51 people.
In 2008, the Indian city of Mumbai came under a bomb attack. India accused the Pakistan-based militant group Lashkar-e-Taiba (LeT) of training, equipping, and financing those responsible for the killings of at least 166 people with support from ?elements? in the Pakistani military.
Islamabad admitted that the attacks were partly planned on its soil, but has firmly denied allegations of any official involvement.
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Source: http://alethonews.wordpress.com/2013/02/22/pakistan-condemns-deadly-bombings-in-india/
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Flipping the 'off' switch on cell growth: Protein uses multiple means to help cells cope when oxygen runs low
Feb. 22, 2013 ? A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying -- known as DNA replication -- and new cell growth to many of the body's functions and in such diseases as cancer.
"We've long known that this protein, HIF-1?, can switch hundreds of genes on or off in response to low oxygen conditions," says Gregg Semenza, M.D., Ph.D., a molecular biologist who led the research team and has long studied the role of low-oxygen conditions in cancer, lung disease and heart disorders. "We've now learned that HIF-1? is even more versatile than we thought, as it can work directly to stop new cells from forming." A report on the discovery appears in the Feb. 12 issue of Science Signaling.
With his team, Semenza, who is the C. Michael Armstrong Professor of Medicine at the Johns Hopkins University School of Medicine's Institute for Cell Engineering and Institute for Genomic Medicine, discovered HIF-1? in the 1990s and has studied it ever since, pinpointing a multitude of genes in different types of cells that have their activity ramped up or down by the activated protein. These changes in so-called "gene expression" help cells survive when oxygen-rich blood flow to an area slows or stops temporarily; they also allow tumors to build new blood vessels to feed themselves.
To learn how HIF-1?'s own activity is controlled, the team looked for proteins from human cells that would attach to HIF-1?. They found two, MCM3 and MCM7, that limited HIF-1?'s activity, and were also part of the DNA replication machinery. Those results were reported in 2011.
In the new research, Semenza and his colleagues further probed HIF-1?'s relationship to DNA replication by comparing cells in low-oxygen conditions to cells kept under normal conditions. They measured the amount of DNA replication complexes in the cells, as well as how active the complexes were. The cells kept in low-oxygen conditions, which had stopped dividing, had just as much of the DNA replication machinery as the normal dividing cells, the researchers found; the difference was that the machinery wasn't working. It turned out that in the nondividing cells, HIF-1? was binding to a protein that loads the DNA replication complex onto DNA strands, and preventing the complex from being activated.
"Our experiments answered the long-standing question of how, exactly, cells stop dividing in response to low oxygen," says Maimon Hubbi, Ph.D., a member of Semenza's team who is now working toward an M.D. degree. "It also shows us that the relationship between HIF-1? and the DNA replication complex is reciprocal -- that is, each can shut the other down."
Share this story on Facebook, Twitter, and Google:
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Story Source:
The above story is reprinted from materials provided by Johns Hopkins Medicine, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- M. E. Hubbi, Kshitiz, D. M. Gilkes, S. Rey, C. C. Wong, W. Luo, D.-H. Kim, C. V. Dang, A. Levchenko, G. L. Semenza. A Nontranscriptional Role for HIF-1? as a Direct Inhibitor of DNA Replication. Science Signaling, 2013; 6 (262): ra10 DOI: 10.1126/scisignal.2003417
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/XQflXj1NWK4/130223111517.htm
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Flipping the 'off' switch on cell growth: Protein uses multiple means to help cells cope when oxygen runs low
Feb. 22, 2013 ? A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying -- known as DNA replication -- and new cell growth to many of the body's functions and in such diseases as cancer.
"We've long known that this protein, HIF-1?, can switch hundreds of genes on or off in response to low oxygen conditions," says Gregg Semenza, M.D., Ph.D., a molecular biologist who led the research team and has long studied the role of low-oxygen conditions in cancer, lung disease and heart disorders. "We've now learned that HIF-1? is even more versatile than we thought, as it can work directly to stop new cells from forming." A report on the discovery appears in the Feb. 12 issue of Science Signaling.
With his team, Semenza, who is the C. Michael Armstrong Professor of Medicine at the Johns Hopkins University School of Medicine's Institute for Cell Engineering and Institute for Genomic Medicine, discovered HIF-1? in the 1990s and has studied it ever since, pinpointing a multitude of genes in different types of cells that have their activity ramped up or down by the activated protein. These changes in so-called "gene expression" help cells survive when oxygen-rich blood flow to an area slows or stops temporarily; they also allow tumors to build new blood vessels to feed themselves.
To learn how HIF-1?'s own activity is controlled, the team looked for proteins from human cells that would attach to HIF-1?. They found two, MCM3 and MCM7, that limited HIF-1?'s activity, and were also part of the DNA replication machinery. Those results were reported in 2011.
In the new research, Semenza and his colleagues further probed HIF-1?'s relationship to DNA replication by comparing cells in low-oxygen conditions to cells kept under normal conditions. They measured the amount of DNA replication complexes in the cells, as well as how active the complexes were. The cells kept in low-oxygen conditions, which had stopped dividing, had just as much of the DNA replication machinery as the normal dividing cells, the researchers found; the difference was that the machinery wasn't working. It turned out that in the nondividing cells, HIF-1? was binding to a protein that loads the DNA replication complex onto DNA strands, and preventing the complex from being activated.
"Our experiments answered the long-standing question of how, exactly, cells stop dividing in response to low oxygen," says Maimon Hubbi, Ph.D., a member of Semenza's team who is now working toward an M.D. degree. "It also shows us that the relationship between HIF-1? and the DNA replication complex is reciprocal -- that is, each can shut the other down."
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by Johns Hopkins Medicine, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- M. E. Hubbi, Kshitiz, D. M. Gilkes, S. Rey, C. C. Wong, W. Luo, D.-H. Kim, C. V. Dang, A. Levchenko, G. L. Semenza. A Nontranscriptional Role for HIF-1? as a Direct Inhibitor of DNA Replication. Science Signaling, 2013; 6 (262): ra10 DOI: 10.1126/scisignal.2003417
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/XQflXj1NWK4/130223111517.htm
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Friday, February 22, 2013
Is Age 25 Too Late To Start Cervical Cancer Screening?
A recent research by the Society of Gynecologic Oncology and the Society of Canadian Colposcopists has claimed that age 25 is perhaps too late to start identifying cervical cancer. It has been said in the SOGC report that there are fair chances that before pap testing is started, precancerous and cancerous lesions have started developing already.
They have apparently suggested that women must start cervical cancer screening at the age of 21 instead and must start going through it every two to three years.
However, the Canadian Task Force on Preventive Health Care, which has unveiled national guidelines in early January, has suggested women to put a gap of three years between screenings, and it must go on till the age of 69.? Though women have been told to go for annual Pap smears, the interval between the screenings has been extended in recent years in some countries.
It has further been shared by Dr. Jennifer Blake, CEO of SOGC, that by identifying lesions in young girls prematurely, such abnormal cells can be removed in the biopsy itself. However, if things get worse, and treatment is the only option then, a large part of an otherwise healthy cervix had to be removed, which affects woman's fertility.
?
Source: http://topnews.net.nz/content/226407-age-25-too-late-start-cervical-cancer-screening
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Why Every Analyst Is In Love With The Siren Song Of The Low-Cost iPhone
For almost as long as Apple's iPhone has been in existence, analysts have claimed to see visions of a low-cost version of the device aimed at developing and prepaid markets. It's easy to see why these visions have grown in magnitude and gained a more vocal following over the years: entering that market would, in theory, broaden Apple's potential appeal by hundreds of millions of new customers. But I refer to the low-cost iPhone as a "siren song" for a reason ? there's a significant potential downside if Apple tries such a device and fails to impress.Source: http://feedproxy.google.com/~r/Techcrunch/~3/JYWCWIgnix4/
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Thursday, February 21, 2013
Air Menzies Int'l opens new division in India
A meeting of like minds at the Combined Logistics Networks annual meeting in Bangkok from May 25-30, 2010, aims to be a good start to rebounding quickly from the impacts of the Global Financial Crisis.
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